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CoursesThe training activities are held both in Milan and Naples. Check out the corresponding schedules:

All Courses

Teacher: R. Visintin - Dates: 9-12 January 2018

Format
1 lecture and 1 practical activity every day

Monday, 7 January, 2019
10.00-11.00

Literature Analysis: How to Read a Paper

R.Visintin - IEO - Milan
Lesson Location: 
Meeting Room 1+2
11.00-12.30

Literature Analysis: How to prepare a Journal Club + Exercise

R.Visintin - IEO - Milan
Lesson Location: 
Meeting Room 1+2
14.00-17.00

Experimental design: critical thinking, protocol writing, data analysis

R.Visintin - IEO - Milan
Lesson Location: 
Meeting Room 1+2
Tuesday, 8 January, 2019
9.30-12.30

How to talk about science: Oral &Poster presentations

R.Visintin - IEO - Milan
Lesson Location: 
Meeting Room 1+2
14.00-15.00

Scientific Writing

R.Visintin - IEO - Milan
Lesson Location: 
Meeting Room 1+2
15.00-16.30

Presentation exercise

R.Visintin - IEO - Milan
Lesson Location: 
Meeting Room 1+2
Friday, 11 January, 2019
9.30-12.30

Group work practical and exercise

R.Visintin - IEO - Milan
Lesson Location: 
Conference Room

Organizer: Ylli Doksani & Marina Mapelli

Dates: 14-18 January 2019

Monday, 14 January, 2019
9.30-13.00

Working with DNA and RNA

- Working with mammalian genomic DNA
  Y. Doksani - IFOM - Milan

- Visualization of DNA recombination intermediates in S. Cerevisiae
  TBD

- Cloning strategies
  TBD

Lesson Location: 
Gold Room
14.00-17.00

- Expression of coding and non-coding genes in mammalian genome
  TBD

- Challenges in measuring RNA expression
  TBD

Lesson Location: 
Gold Room
Tuesday, 15 January, 2019
9.30-13.00

Genetic engineering

- Fundamentals of gene targeting
  TBD

- Gene therapy of genetic diseases: from the bench to the bedside
  TBD

Lesson Location: 
Gold Room
14.00-17.00

- CRISPR technology and its applications in drug discovery
  TBD

Protein Biochemistry

- Working with antibodies
  S.Polo - IFOM - Milan

Lesson Location: 
Gold Room
Wednesday, 16 January, 2019
9.30-12.30

Protein Biochemistry

- Protein expression
  M. Mapelli  - IEO - Milan

- Measuring protein interactions in vitro 
  M. Mapelli - IEO - Milan

Lesson Location: 
Gold Room
16.00-17.30

Measuring protein interactions in vivo
TBD

Lesson Location: 
Gold Room
Thursday, 17 January, 2019
15.00-18.00

Protein Biochemistry

- Capturing specific protein–DNA interactions in biological systems by Chromatin Immunoprecipitation
  TBD

- Protein-DNA interactions involved in DNA repair and DNA replication 
  TBD

Lesson Location: 
Gold Room
Friday, 18 January, 2019
9.30-13.00

Protein Biochemistry

- Principles of enzymology
  TBD

- Biochemistry of Ubiquitin
  TBD

Lesson Location: 
Gold Room
14.00-15.30

Genetic engineering

- Targeted (epi)genome editing and cell therapy applications
  TBD

Lesson Location: 
Gold Room
15.30-17.30

- Case studies

Lesson Location: 
Gold Room

Dates: 21-23 January 2019

The course will cover all basic microscopy techniques and provide an overview of a broad range of innovative imaging approaches. Each lecture will include an overview of the topic and a presentation of the lecturer’s specific field of interest.

Monday, 21 January, 2019
9.00-13.00

-Introduction to the course
 
-Basic principles of microscopy
 
- Overview of the different types of  microscopy and their applications
  

Lesson Location: 
Meeting Room 1+2
14.00-16.00

-Nuclear imaging: from repositioning to polarity  acquisition
 

Tuesday, 22 January, 2019
9.00-13.00

-Sample preparation for fluorescence microscopy

-Membrane trafficking imaging: from in vitro to in vivo studies
 

Lesson Location: 
Meeting Room 1+2
14.00-15.15

-Imaging in small animal: from worm to zebrafish to mice, application for cancer
 

Lesson Location: 
Meeting Room 1+2
Wednesday, 23 January, 2019
9.00-13.00

-Basic principles of Flow Cytometry and Fluorescence Activated Cell Sorting
 
-How to analyse my images: from image J to matlab, velocity

-Practicals on image analysis
 

Lesson Location: 
Meeting Room 1+2
14.00-16.00

Plasma membrane dynamics and mechanobiology during cell shape changes in health and disease
 

Lesson Location: 
Meeting Room 1+2
16.15-17.00

Concluding remarks and closure
 

Lesson Location: 
Meeting Room 1+2

Organizer: F. Ambrogi, University of Milan - Dates: 24-31 January 2019

The course will introduce the basic statistical tool and concepts of descriptive and inferential statistics. The lectures will be based on the book “Data Analysis for the Life Sciences with R”.  The learning approach will also be through the direct use of the software “to relate the concepts to data analysis”. The book used for the course focuses on the use of the computer for doing data analysis rather than on mathematics. However some mathematical aspects will be explained to get better intuition of the algorithms behind the software itself. During the course the free R software will be introduced. Students are required to bring their own laptops with the most recent version of R installed.

 

Thursday, 24 January, 2019
9.30-11.00

Introduction to descriptive statistics: distributions and their representation; summary measures of position and dispersion. 

F.Ambrogi UNIMI
11.30-13.00

Plots to avoid.

F.Ambrogi UNIMI
14.00-16.00

Probablity and diagnostic tests.

F.Ambrogi UNIMI
Lesson Location: 
Meeting Room 1+2
Friday, 25 January, 2019
9.30-11.00

Introduction to statistical inference: Random Variables, the Null Hypothesis, Distributions, Sampling and the Central Limit Theorem.

F.Ambrogi UNIMI
11.30-13.00

Testing statistical significance and building confidence intervals.

F.Ambrogi UNIMI
14.00-16.00

Exercises

F.Ambrogi UNIMI
Lesson Location: 
Meeting Room 1+2
Tuesday, 29 January, 2019
9.30-13.00

Introduction to the R software

14.00-16.00

Introduction to the R software

Wednesday, 30 January, 2019
9.30-11.00

Association tests.

F.Ambrogi UNIMI
Lesson Location: 
Meeting Room 1+2
11.30-13.00

Matrix Algebra.

F.Ambrogi UNIMI
Lesson Location: 
Meeting Room 1+2
14.00-16.00

Linear Models: the Design Matrix, standard errors, interactions, collinearity, confounding.

F. Ambrogi UNIMI
Lesson Location: 
Meeting Room 1+2
Thursday, 31 January, 2019
9.30-11.00

Exercises on the linear model. 

F.Ambrogi UNIMI
11.30-13.00

A short introduction to survival analysis

F.Ambrogi UNIMI
14.00-16.00

Exercise on survival analysis

F.Ambrogi UNIMI
Lesson Location: 
Meeting Room 1+2

Organizers: D.Pasini, A. Bachi, T. Bonaldi - Dates: 04-11 February 2019

Monday, 4 February, 2019
9.30-11.00

Introduction to genomics

Pasini Diego
Lesson Location: 
Gold Room
11.00-12.45

Epigenomics and transcriptomics

Lesson Location: 
Gold Room
15.30-17.00

Practicals and Journal Club

Lesson Location: 
Genomic unit and Gold room
Tuesday, 5 February, 2019
9.30-10.45

Non-coding Genome

Lesson Location: 
Gold Room
11.00-1215

Single Cell Analyses

Lesson Location: 
Gold Room
14.30-16.30

Practicals and Journal Club

Lesson Location: 
Genomic unit and Gold room
Wednesday, 6 February, 2019
9.30-11.00

Computational Approaches for NGS data

Lesson Location: 
Gold Room
Thursday, 7 February, 2019
9.30-11.00

Introduction to MS proteomics

Bachi Angela
Lesson Location: 
Gold Room
11.15-12.45

Quantitative Proteomics

Lesson Location: 
Gold Room
15.00-17.30

Practical tutorials for 4 groups - Part 1

Lesson Location: 
Gold Room
Friday, 8 February, 2019
9.30-11.00

Targeted proteomics

Bachi Angela
Lesson Location: 
Gold Room
11.15-12.45

Proteomics in epigenetic research

Bonaldi Tiziana
Lesson Location: 
Gold Room
14.00-15.00

Proteomics in clinical research and drug discovery

Lesson Location: 
Gold Room
15.00-17.30

Practical tutorials for 4 groups - Part 2

Lesson Location: 
tbd
Monday, 11 February, 2019
9.30-11.00

Proteomics and Systems biology

Lesson Location: 
Gold Room
11.15-12.45

Large-scale data analysis for -omics studies

Lesson Location: 
Gold Room

Dates: 12-15 February 2019

 

Organizer: Francesco Ferrari IFOM, MIlan

The course will include both theory classes and hands on tutorials to cover different research topics requiring bioinformatics solutions.
The first day will focus on key concepts of nucleic acids and protein sequences analysis.
Then a second part of the course will be focused on bioinformatics for transcriptomics, epigenomics and cancer genomics data analysis. This part will try to address bioinformatics problems that many of the SEMM students will encounter during their research activity, thus it will cover a larger portion of the course.
Finally, the last part of the course will comprise two lectures on a few more specialistic topics such as transcription dynamics and chromatin 3D architecture. These are meant to provide an overview over emerging and more specialistic fields where bioinformatics plays a key role. These latter two lectures will be only theory classes.

 

 

Tuesday, 12 February, 2019
9.20-9.30

Course introduction

Francesco Ferrari - IFOM
Lesson Location: 
Meeting room 1-2
9.30-13.00

Sequence databases and alignments

Lesson Location: 
Meeting room 1-2
14.00-17.30

Protein sequence analysis

Lesson Location: 
Meeting room 1-2
Wednesday, 13 February, 2019
9.30-13.00

Annotating regulatory elements in genomic sequences

Lesson Location: 
Meeting room 1-2
14.00-17.30

Transcriptomics in cancer research: bulk and single cell analysis

Lesson Location: 
Meeting room 1-2
Thursday, 14 February, 2019
9.30-13.00

Transcriptomics in cancer research: bulk and single cell analysis (part 2)

Lesson Location: 
Meeting room 1-2
14.45-18.15

Epigenomics data analysis

Lesson Location: 
Meeting room 1-2
Friday, 15 February, 2019
9.30-13.00

Cancer pharmacogenomics data integration, resources and tools

Lesson Location: 
Meeting room 1-2
15.00-16.30

(epi)transcriptional dynamics

Lesson Location: 
Meeting room 1-2
16.30-18.00

Chromatin 3D architecture data analysis

Lesson Location: 
Meeting room 1-2
Wednesday, 29 November, 2017

Organizer: Myriam Alcalay & Ugo Cavallaro IEO Milan

Dates: 18-20 February 2019

 

Program to be communicated

Monday, 18 February, 2019
9.15-12.15

Approaches for the discovery of genetic abnormalities in cancer

9.15-10.45

Introduction to the course

Alcalay Myriam
Lesson Location: 
Gold Room
9.30-10.45

Genomics and big data, from science to medicine and back

Tonon Giovanni -HSR - Milan
Lesson Location: 
Gold Room
11.00-12.15

Genetic screens

Lanfrancone Luisa
Lesson Location: 
Gold Room
14.00-16.00

Journal Club

Lesson Location: 
Gold Room
Tuesday, 19 February, 2019
9.30-12.15

Issues in Cancer Genetics

9.30-10.45

Cancer stem cell genetics

Testa Giuseppe
Lesson Location: 
Gold Room
11-12.15

Viral oncogenesis

Chiocca Susanna
Lesson Location: 
Gold Room
14.00-16.00

Journal Club

Lesson Location: 
Gold Room
Wednesday, 20 February, 2019
9.30-12.15

Translational aspects of Cancer Genetics

9.30-10.45

  How the environment affects cancer genomics

Mazzarella Luca - IEO - Milan
Lesson Location: 
Gold Room
11.00-12.15

Translational and therapeutic implications of tumor heterogeneity

Trusolino Livio - University of Turin
Lesson Location: 
Gold Room
14.00-16.45

Cancer Genetics in medical practice

14.00-15.15

Cancer genetics in the clinic: implications and applications

Bonanni Bernardo - IEO - Milan
Lesson Location: 
Gold Room
15.30-16.45

Perspectives of clinically oriented cancer genetics

Di Fiore Pier Paolo

Organizer: Myriam Alcalay

Dates: 25-28 February 2019

Friday, 25 January, 2019
9.30-12.30

Principles of Effective Writing

M.Alcalay - IEO - Milan
Lesson Location: 
Meeting room 1-2
15.00-16.00

Grammar in Scientific English

M.Alcalay - IEO - Milan
Lesson Location: 
Meeting Room 1+2
16.00-18.00

Exercises

M.Alcalay - IEO - Milan
Lesson Location: 
Meeting Room 1+2
Tuesday, 26 February, 2019
9.30-11.30

Writing an original manuscript

M.Alcalay - IEO - Milan
Lesson Location: 
Meeting Room 1+2
11.45-12.45

Plagiarism and Copyrights

M.Alcalay - IEO - Milan
Lesson Location: 
Meeting Room 1+2
14.00-16.00

Exercises: re-write your abstract

Lesson Location: 
Meeting Room 1+2
Thursday, 28 February, 2019
14.00-16.00

  Abstracts: before/after

M.Alcalay - IEO - Milan
Lesson Location: 
Meeting Room 1+2

Organizer: M. Mapelli - Dates: 8-10 April 2019

Format
3-days course

The course is co-organized with the Molecular and Cellular Biology PhD program of the Department of Bioscience of Milan University. 

The course will focus on how to analize the structures and on structural biology projects. There will be a day dedicated to  Cryo-EM with practicals at the microscope.

Monday, 8 April, 2019
9.00-10.30

Lectures on structures and crystal structure determination 

Mapelli Marina
Lesson Location: 
tbd
11.00-12.30

Crystallization tutorial

Sebastiano Pasqualato IEO
Lesson Location: 
tbd
14.00-15.00

Structural biology assisted drug design 

Ilaria Ferlenghi GSK Siena
Lesson Location: 
tbd
Tuesday, 9 April, 2019
9.00-10.30

Lectures on Cryo-EM theory

TBD
Lesson Location: 
tbd
11.00-12.00

Cryo-EM seminar

Dr. J.M. Carazo (Madrid)
Lesson Location: 
tbd
14.30-17.00

Cryo-EM practicals

Lesson Location: 
tbd
Wednesday, 10 April, 2019
9.30-11.00

  Cryo-EM seminar

Alessandro Costa – Francis Crick Institute of London
Lesson Location: 
tbd
11.00-12.30

Tutorial: Looking at structures, Pymol II

TBD
Lesson Location: 
tbd