With the onsite programme paused, many of our events are now being offered in virtual formats.
The SEMM Technological Roundtables, hosted on GoToWebinar platform, are free to attend, but you need to register for a place beforehand, usign the “REGISTER” button below.
Once registered, you will receive a confirmation email with a link to join the Roundtable.
We wait for you in great number!
The next Roundtable will be:
SEMM Technological Roundtable: "Structural and Conformational Proteomics and their Impact in Life Science"
December 3, 2021 – h. 2.45 p.m.
Structural and conformational mass spectrometry (MS) proteomics methods are undergoing an explosion in their application to study proteins and protein complexes, thanks to its current applicability to many different protein types, including not only structured proteins, but also particularly challenging ones, such as intrinsically disordered proteins, integral membrane proteins and multiprotein complexes.
Structural MS methods are able to capture transient interactions, can be used to study proteins and complexes up to the megadalton range, and can discern interactions in complex mixtures such as whole cell lysates and even intact cells. In native MS analysis large biomolecules and complexes are analyzed using experimental conditions so mild that their non-covalent interactions, native state and associated biological functionality are preserved.
These methods coupled other technologies such as cryo-electron microscopy provide a knowledge base that is changing the face of structural biology, impacting various disciplines in life science, from medicinal chemistry, molecular pharmacology to neurobiology, developmental biology, immunology and molecular medicine.
Proponents and Chair Persons
European Institute of Oncology, Milan, Italy
Human Technopole, Milan, Italy
"Biological Mass Spectrometry – Measuring More than Mass"
Michael Barber Centre for Collaborative Mass Spectrometry Manchester Institute of Biotechnology, The University of Manchester, Manchester, UK
For further information please visit: Prof. Perdita Barran
"Proteome-wide Limited Proteolysis"
Max-Delbrück Center for Molecular Medicine, Berlin, Germany
REGISTER click here [link to an external website]
ATTENDEES GUIDELINES (some info about how to connect and act as attendee during our Roundtable)
For information: roundtables[AT]semm.it - phone: +39 02 94375037