7-10 March 2016 Mon, 07/03/2016 Milan Organizer: Paolo Bruzzi, H San Martino, GE Dates: 7-10 March 2016 Monday, 07 March 2016 Timetable 11.00-13.00 Lesson Argument Medicine & Statistics Traditional Medical Thinking Medical Determinism and its crisis How to evaluate the effects of a treatment. Timetable 14.30-17.00 Lesson Argument Clinical Trial The perfect study Conceptual Basis of medical statistics: sampling error and bias Phases of Clinical Trials Activity vs Efficacy Lesson Location Gold Room Tuesday, 08 March 2016 Timetable 9.00-12.30 Lesson Argument Main Features of the Randomised Clinical trial Internal Validity of a study Observational vs experimental studies Timetable 14.00-15.00 Lesson Argument External validity of a study Lesson Location Ivory Room Wednesday, 09 March 2016 Timetable 11.00-13.00 Lesson Argument The Statistical Plan of a clinical study Multiplicity (Multiple Endpoints/Interim Analyses/Subgroup Analyses) Timetable 14.30-17.00 Lesson Argument Evaluation of Risk and Prediction of Efficacy of a treatment Surrogate endpoints and markers Clinical Studies in rare diseases Lesson Location Ivory Room Thursday, 10 March 2016 Timetable 9.00-12.30 Lesson Argument Observational Studies Ecological vs Analytic Studies Types and Main features of observational studies Timetable 14.00-15.00 Lesson Argument Evidence Based Medicine General Concepts Systematic Reviews/Pooled analyses vs Medical Decision Lesson Location Diamond Room