Spatiotemporal dynamics of the genome and the transcriptome

15-16 July 2025
Milan

Organizer: Beatrice Bodega (INGM) - Dates: 15-16 July 2025

Location: INGM, c/o Padiglione Invernizzi, Via Francesco Sforza, 35, Milan

Aim of the course: The course offers an in-depth exploration of the mechanisms regulating cellular processes in complex organisms, both in health and disease. It highlights the roles of cell plasticity and adaptability in maintaining cellular homeostasis and responding to environmental cues. The genome is presented as the central input, with its structure and function ensuring cell identity and regulating transcription through a diverse array of interconnected epigenetic mechanisms. Key topics include genome integrity, transcriptional regulation, three-dimensional organization, and nuclear compartmentalization, all of which are dynamic, quantitative factors that operate at the single-cell level to govern tissue organization and specialization.

Timetable
8.30-10.30
Lesson Argument

Genome and transcriptome organization and regulation

Teachers

Beatrice Bodega,

Affiliations

INGM

Lesson Location
INGM Conference Room
Timetable
10.30-12.30
Lesson Argument

TBD

Teachers

Beatrice Bodega,

Affiliations

INGM

Lesson Location
INGM Conference Room
Timetable
13.30-15.30
Lesson Argument

Spatiotemporal regulation of gene expression: from description to perturbation and back

Teachers

Ivano Legnini,

Affiliations

Human Technopole

Lesson Location
INGM Conference Room
Timetable
8.30-10.30
Lesson Argument

TBD

Teachers

Beatrice Bodega,

Affiliations

INGM

Lesson Location
INGM Conference Room
Timetable
10.30-12.30
Lesson Argument

Cell type-specific intronic RNAs shape genome architecture during neuronal lineage specification

Teachers

Magda Bienko,

Affiliations

Human Technopole

Lesson Location
INGM Conference Room